Publications

1) (in press) Khosravi, S., Li, R., Cai, X., Melo, L. & Ranjbar, A. (2025) Ferroptosis-Targeting Drugs for Critical Diseases. Current Drug Therapy 

2) Melo, L. (2025) Male Contraceptives: Why Haven’t They Taken Off Yet? A Comprehensive Review. Brazilian Journal of Clinical Medicine and Review. 2025:Jan-Dec; 03(1): bjcmr. https://www.bjclinicalmedicinereview.com.br/index.php/bjcmr/article/view/bjcmr34

3) Melo, L., Bolster, D., Kalgaonkar, S., D’Adamo, C.,L., Treadway, S., Chinta, S., Bloor, S., Black, H., Coy, E., Hobson, A. & Chae, L. (2025) Effects of N-Trans Caffeoyltyramine (NCT) and N-Trans Feruloyltyramine (NFT) Supplementation in Individuals with Diarrhea Predominant-Irritable Bowel Syndrome (IBS-D): Results from a Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. https://www.ffhdj.com/index.php/BioactiveCompounds/article/view/1655

4) Khosravi, S., Li, R., Cai, X., Melo, L., Ranjbar, A. & Chae, L. (2025) Ferroptosis: A New Avenue in Drug Development. (in print)

5) Jupianez-Merly, C., Jencks, K., Dilmaghani, S., Ferber, M., Melo, L., Kliken, JW., Kalgaonkar, S., & Camileri, M. (2024) A pilot study of Hemp Hull Bio Gut Fiber (BGF) to Reduce Intestinal Permeability in IBS-BAD. Alimentary Pharmacology & Therapeutics. https://doi.org/10.1111/apt.18164

6) Book Chapter: Melo, L.,  Babayev, M., Vanin, J., Ranjbar, A. & Klaunig, JE. (2024) Occupational Chemical Carcinogenesis. In: Patty’s Toxicology, 7th Edition. Wiley Press. ISBN: 978-1-119-63416-4

7) Book Chapter: Babayev, M., Melo, L. & Klaunig, JE., (2023) Detection and Evaluation of Chemically Induced Liver Injury. In: Wallace Hayes, Claire L. Kruger Principles and Methods of Toxicology 7th ed. CRC Press.

8) Jeon, S., Scorletti, E., Buyco, D., Lin, C., Saiman, Y., Martin, J., Hooks, R., Ogretmen, B., Argemi, J., Melo, L., Bataller, L. & Carr, R. M. (2022). Ceramide synthase 6 (CerS6) promotes alcohol-induced fatty liver by promoting metabolic dysfunction and upregulating lipid droplet-associated proteins. bioRxiv, 2022-11.
https://europepmc.org/article/ppr/ppr567067

9) Ma, X , Chen, A , Melo, L, et al. (2022) Loss of hepatic DRP1 exacerbates alcoholic hepatitis by inducing megamitochondria and mitochondrial maladaptation. Hepatology. https://doi.org/10.1002/hep.32604

10) Ma, J., Guillot, A., Yang, Z., Mackowiak, B., Hwang, S., Park, O., Peiffer, B.J., Ahmadi, A.R., Melo, L, et al. (2022) Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure. The Journal of Clinical Investigation, 132(14).
https://doi.org/10.1172/JCI157780

11) Gómez-Medina, C, Melo, L, Martí-Aguado, D, Bataller, R (2022) Subclinical versus advanced forms of alcohol-related liver disease: need for early detection. Clinical and Molecular Hepatology.
https://doi.org/10.3350/cmh.2022.0017

12) Book Chapter: Klaunig, JE,  Melo, L. & Tilmant, K., (2022) Chemical Carcinogenesis. In: Roberts, Stephen M., Robert C. James, and Phillip L. Williams. Principles of toxicology: environmental and industrial applications. 4^th ed. John Wiley & Sons.
Amazon Link

13) Melo, L., Hagar, A. & Klaunig, JE. (2022) Gene Expression Signature of Exercise and Change of Diet on Non-alcoholic Fatty Liver Disease in Mice. Comparative Exercise Physiology, 8(2), 143-154. https://doi.org/10.3920/CEP210033

14) Guomao, Z., Melo, L., Chakraborty, R., Klaunig, JE. & Salamova, A. (2022) Biotransformation of 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine (TTBP-TAZ) can contribute to high levels of 2,4,6-tribromophenol (2,4,6-TBP) in humans. Environment International, 158. 106943. https://doi.org/10.1016/j.envint.2021.106943

15) Melo, L. (2021) Women in Toxicology in the United States, Toxicology Research, 2021;, tfab075, https://doi.org/10.1093/toxres/tfab075

16) E- Book: Melo, L. But After All, What is Quantum Physics? An informal conversation. ISBN: 978-65-00-00844-9 (available in English and Portuguese) https://lumamelo.com/contact/

17) Melo, L., Bilici, M., Hagar, A. & Klaunig, JE. (2021) The Effects of Endurance Exercise on High Fat Diet Induced Non-Alcoholic Fatty Liver Disease in Mice. Physiological Reports. 9(15) https://doi.org/10.14814/phy2.14926

18) Melo, L. & Melo, T.S. (2021) Pioneer women in the development of toxicology in Brazil. Brazilian Journal of Medical and Biological Research, 54(5). https://www.scielo.br/scielo.php?pid=S0100-879X2021000500451&script=sci_arttext

19) Melo, L. (2021). Psychosomatic as we know. Academia Letters, Article 3145. https://doi.org/10.20935/AL3145

20) Melo, L., Tilmant, K., Hagar, A., & Klaunig, J. E. (2020). Effect of Endurance Exercise Training on Liver Gene Expression in Male and Female Mice. Applied Physiology, Nutrition, and Metabolism, (ja). https://cdnsciencepub.com/doi/10.1139/apnm-2020-0379?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

21) Klaunig, JE., Melo, L., Tilmant, K. (2020). Mechanisms of Hepatic Cancer by Persistent Organic Pollutants (POPs). Current Opinion in Toxicology, 19(105-111) https://www.sciencedirect.com/science/article/pii/S2468202020300097?dgcid=coauthor

22) Hagar, A., Melo, L., Hills, G., Kenshur, N., & Dickinson, S. (2019). A new aerobic fitness score based on lactate sensing during sub-maximal exercise. Applied Physiology, Nutrition, and Metabolism. 45(7): 784-792. https://www.nrcresearchpress.com/doi/abs/10.1139/apnm-2019-0739#.XnDpSahKhPa

23) Melo, L., & Hagar, A. (2019). How to train a mouse-methodological issues in pre-clinical exercise oncology. American journal of cancer research, 9(6), 1246. http://www.ajcr.us/files/ajcr0096653.pdf

24) Hagar, A., Wang, Z., Koyama, S., Serrano, J. A., Melo, L., Vargas, S., … & Foley, J. (2019). Endurance training slows breast tumor growth in mice by suppressing Treg cells recruitment to tumors. BMC Cancer, 19(1), 536. https://bmccancer.biomedcentral.com/articles/10.1186/s12885-019-5745-7

24) Raw, J., Melo, L. O., & Barbosa, L. R. (2017). On the Interaction of Alkyl-Functionalized Ionic Liquids with Model Proteins: A Spectroscopic and Structural Study. Biophysical Journal, 112(3), 190a. https://www.cell.com/biophysj/pdf/S0006-3495(16)32086-0.pdf

25) Melo, L. & Pessoa Jr, O. (2015). Causal Events of Molecular Motors. In: Ahumada, J.V.; Venturelli, A.N.; Chibeni, S.S.. (Org.). Filosofia e Historia de la Ciencia en el Cono Sur. 1ed.Córdoba: Editoral de la UNC, p. 489. https://www.researchgate.net/publication/322343387_Causal_Events_of_Molecular_Motors

26) Book Chapter: Melo, L. & Pessoa Jr, O. (2015). The interacionist dualism doesn’t have to violate the physics´ conservation laws. In: Aiub, M.; Gonzalez, M.E.Q. & Broens, M.C.. (Org.). Filosofia da Mente, Ciência Cognitiva e o pós-humano: para onde vamos?. 1ed.São Paulo: FiloCzar,, p. 119-122. https://www.editorafiloczar.store/produto/41399/filosofia-da-mente-ciencia-cognitiva-e-o-pos-humano-para-onde-vamos